Our current focus is on the use of caloric restriction and exercise to prevent breast cancer.

Caloric restriction is the most powerful, physiological, non detrimental approach to cancer prevention that has ever been identified.

Physical inactivity has recently been implicated as a major factor influencing cancer risk in human populations around the world.

We are determining the chemical basis underlying the potent preventive activity of weight control and physical activity so that we can use the knowledge to develop practical, safe and effective approaches to prevent cancer and other diseases.